Xbp1 protein (Ictidomys tridecemlineatus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

Xbp1

BZIP domain-containing protein. (351 aa)

Predicted Functional Partners:

ERN1

0.939

FAU

0.935

Ddit3

0.894

ENSSTOP00000032126

0.894

Ern2

0.889

TBP

0.872

TBPL2

0.872

ATF6B

0.868

RNASEL

0.867

TBPL1

0.863

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF6B	Ddit3	ENSSTOP00000029244	ENSSTOP00000016331	Activating transcription factor 6 beta.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.865
ATF6B	ENSSTOP00000032126	ENSSTOP00000029244	ENSSTOP00000032126	Activating transcription factor 6 beta.	Uncharacterized protein.	0.865
ATF6B	ERN1	ENSSTOP00000029244	ENSSTOP00000008139	Activating transcription factor 6 beta.	Endoplasmic reticulum to nucleus signaling 1.	0.531
ATF6B	Ern2	ENSSTOP00000029244	ENSSTOP00000011128	Activating transcription factor 6 beta.	Endoplasmic reticulum to nucleus signaling 2.	0.531
ATF6B	RNASEL	ENSSTOP00000029244	ENSSTOP00000006563	Activating transcription factor 6 beta.	Uncharacterized protein.	0.562
ATF6B	Xbp1	ENSSTOP00000029244	ENSSTOP00000003732	Activating transcription factor 6 beta.	BZIP domain-containing protein.	0.868
Ddit3	ATF6B	ENSSTOP00000016331	ENSSTOP00000029244	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Activating transcription factor 6 beta.	0.865
Ddit3	ERN1	ENSSTOP00000016331	ENSSTOP00000008139	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Endoplasmic reticulum to nucleus signaling 1.	0.451
Ddit3	FAU	ENSSTOP00000016331	ENSSTOP00000002981	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.412
Ddit3	Xbp1	ENSSTOP00000016331	ENSSTOP00000003732	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	BZIP domain-containing protein.	0.894
ENSSTOP00000032126	ATF6B	ENSSTOP00000032126	ENSSTOP00000029244	Uncharacterized protein.	Activating transcription factor 6 beta.	0.865
ENSSTOP00000032126	ERN1	ENSSTOP00000032126	ENSSTOP00000008139	Uncharacterized protein.	Endoplasmic reticulum to nucleus signaling 1.	0.451
ENSSTOP00000032126	FAU	ENSSTOP00000032126	ENSSTOP00000002981	Uncharacterized protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.412
ENSSTOP00000032126	Xbp1	ENSSTOP00000032126	ENSSTOP00000003732	Uncharacterized protein.	BZIP domain-containing protein.	0.894
ERN1	ATF6B	ENSSTOP00000008139	ENSSTOP00000029244	Endoplasmic reticulum to nucleus signaling 1.	Activating transcription factor 6 beta.	0.531
ERN1	Ddit3	ENSSTOP00000008139	ENSSTOP00000016331	Endoplasmic reticulum to nucleus signaling 1.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.451
ERN1	ENSSTOP00000032126	ENSSTOP00000008139	ENSSTOP00000032126	Endoplasmic reticulum to nucleus signaling 1.	Uncharacterized protein.	0.451
ERN1	FAU	ENSSTOP00000008139	ENSSTOP00000002981	Endoplasmic reticulum to nucleus signaling 1.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.414
ERN1	Xbp1	ENSSTOP00000008139	ENSSTOP00000003732	Endoplasmic reticulum to nucleus signaling 1.	BZIP domain-containing protein.	0.939
Ern2	ATF6B	ENSSTOP00000011128	ENSSTOP00000029244	Endoplasmic reticulum to nucleus signaling 2.	Activating transcription factor 6 beta.	0.531