STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)    
Predicted Functional Partners:
EED
Embryonic ectoderm development.
    
 0.979
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.979
Kmt5a
SET domain-containing protein.
   
 0.920
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.908
WDR73
WD repeat domain 73.
    
 0.902
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.902
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.902
KDM6B
Lysine demethylase 6B.
   
 0.897
KDM6A
Lysine demethylase 6A.
   
 0.897
KMT2E
Lysine methyltransferase 2E.
   
 0.886
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.