STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEDEmbryonic ectoderm development. (441 aa)    
Predicted Functional Partners:
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.999
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 0.998
JARID2
Jumonji and AT-rich interaction domain containing 2.
    
 0.997
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
    
 0.994
AEBP2
AE binding protein 2.
    
 0.994
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.993
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.993
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
    
 0.979
WDR73
WD repeat domain 73.
    
 0.978
KDM6A
Lysine demethylase 6A.
    
 0.969
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.