STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (761 aa)    
Predicted Functional Partners:
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.994
LOC101967288
Uncharacterized protein.
    
 0.990
FSHB
Follicle stimulating hormone subunit beta.
   
 0.989
CGA
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
    
 0.964
POMC
Proopiomelanocortin.
   
 
 0.962
LOC101978140
Luteinizing hormone beta subunit.
   
 0.962
CRH
Corticotropin releasing hormone.
     
 0.959
ADCYAP1
Adenylate cyclase activating polypeptide 1.
     
 0.959
I3MA50_ICTTR
Uncharacterized protein.
     
  0.956
GPHA2
Glycoprotein hormone subunit alpha 2.
    
 0.956
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.