STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POMCProopiomelanocortin. (212 aa)    
Predicted Functional Partners:
MC2R
Melanocortin 2 receptor.
    
 0.997
MC4R
Melanocortin 4 receptor.
    
 0.995
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.994
Mrap
Uncharacterized protein.
    
 0.992
I3NH06_ICTTR
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.983
LOC101962180
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.983
LPAR3
Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.980
MC5R
Melanocortin 5 receptor.
    
 0.970
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.969
MC3R
Melanocortin 3 receptor.
    
 0.948
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.