HSPA9 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACO2	ATP5F1A	ENSSTOP00000028500	ENSSTOP00000029590	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.996
ACO2	DNAJA3	ENSSTOP00000028500	ENSSTOP00000000410	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	DnaJ heat shock protein family (Hsp40) member A3.	0.480
ACO2	GRPEL1	ENSSTOP00000028500	ENSSTOP00000008767	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.485
ACO2	HSPA9	ENSSTOP00000028500	ENSSTOP00000007876	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.985
ACO2	Hspa5	ENSSTOP00000028500	ENSSTOP00000010092	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.419
ACO2	I3N7W8_ICTTR	ENSSTOP00000028500	ENSSTOP00000020464	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.915
ACO2	ISCU	ENSSTOP00000028500	ENSSTOP00000002142	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.711
ACO2	TIMM44	ENSSTOP00000028500	ENSSTOP00000020003	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.468
ATP5F1A	ACO2	ENSSTOP00000029590	ENSSTOP00000028500	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.996
ATP5F1A	GRPEL1	ENSSTOP00000029590	ENSSTOP00000008767	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.444
ATP5F1A	HSPA9	ENSSTOP00000029590	ENSSTOP00000007876	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.987
ATP5F1A	Hspa5	ENSSTOP00000029590	ENSSTOP00000010092	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.925
ATP5F1A	I3N7W8_ICTTR	ENSSTOP00000029590	ENSSTOP00000020464	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.995
ATP5F1A	TIMM44	ENSSTOP00000029590	ENSSTOP00000020003	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.836
ATP5F1A	TRAP1	ENSSTOP00000029590	ENSSTOP00000004451	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	TNF receptor associated protein 1.	0.687
DNAJA3	ACO2	ENSSTOP00000000410	ENSSTOP00000028500	DnaJ heat shock protein family (Hsp40) member A3.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.480
DNAJA3	GRPEL1	ENSSTOP00000000410	ENSSTOP00000008767	DnaJ heat shock protein family (Hsp40) member A3.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.898
DNAJA3	HSPA9	ENSSTOP00000000410	ENSSTOP00000007876	DnaJ heat shock protein family (Hsp40) member A3.	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.	0.993
DNAJA3	Hspa5	ENSSTOP00000000410	ENSSTOP00000010092	DnaJ heat shock protein family (Hsp40) member A3.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.867
DNAJA3	I3N7W8_ICTTR	ENSSTOP00000000410	ENSSTOP00000020464	DnaJ heat shock protein family (Hsp40) member A3.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.780