STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN1Actinin alpha 1. (892 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.993
ACTN4
Actinin alpha 4.
  
0.993
ZYX
Zyxin.
   
 0.929
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
 0.926
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.912
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 0.899
Itgb3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.890
ITGB4
Integrin beta.
    
 0.879
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 
 0.877
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.876
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.