STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLRC5NLR family CARD domain containing 5. (1847 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.967
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.948
MAVS
Mitochondrial antiviral signaling protein.
    
 0.804
TAP1
Transporter 1, ATP binding cassette subfamily B member.
   
  
 0.797
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 0.775
PYCARD
PYD and CARD domain containing.
   
 0.765
IFIH1
Interferon induced with helicase C domain 1.
   
 0.760
DDX58
DExD/H-box helicase 58.
   
 0.760
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.756
Nlrp1
NLR family pyrin domain containing 1.
    
0.748
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.