STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFPITissue factor pathway inhibitor. (301 aa)    
Predicted Functional Partners:
F10
Coagulation factor X.
    
 0.957
F7
Coagulation factor VII; Belongs to the peptidase S1 family.
    
 0.955
F9
Coagulation factor IX.
    
 0.877
LOC101960778
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.808
LOC101968603
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.808
LOC101966300
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.808
LOC101966003
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.808
LOC101966592
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.808
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
     
 0.779
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.766
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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