STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS48Serine protease 48; Belongs to the peptidase S1 family. (314 aa)    
Predicted Functional Partners:
MST1R
Macrophage stimulating 1 receptor.
    
  0.768
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.768
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.641
WDR90
WD repeat domain 90.
    
 
 0.566
NOS1AP
Nitric oxide synthase 1 adaptor protein.
      
 0.523
SNED1
Sushi, nidogen and EGF like domains 1.
    
  0.491
SH3D19
SH3 domain containing 19.
      
 0.459
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
    
  0.453
ENSSTOP00000029895
WAP domain-containing protein.
    
 0.448
SPINK6
Serine peptidase inhibitor, Kazal type 6.
    
  0.444
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.