HDAC2 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	Chd4	ENSSTOP00000015560	ENSSTOP00000006839	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.999
CHD3	ENSSTOP00000026639	ENSSTOP00000015560	ENSSTOP00000026639	Chromodomain helicase DNA binding protein 3.	Hist_deacetyl domain-containing protein.	0.992
CHD3	HDAC2	ENSSTOP00000015560	ENSSTOP00000011457	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
CHD3	Hdac1	ENSSTOP00000015560	ENSSTOP00000010833	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.992
CHD3	MTA1	ENSSTOP00000015560	ENSSTOP00000007254	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.998
CHD3	MTA2	ENSSTOP00000015560	ENSSTOP00000002588	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.998
CHD3	RCOR1	ENSSTOP00000015560	ENSSTOP00000020809	Chromodomain helicase DNA binding protein 3.	REST corepressor 1.	0.799
CHD3	SAP30	ENSSTOP00000015560	ENSSTOP00000019204	Chromodomain helicase DNA binding protein 3.	Sin3A associated protein 30.	0.759
CHD3	SIN3A	ENSSTOP00000015560	ENSSTOP00000015334	Chromodomain helicase DNA binding protein 3.	SIN3 transcription regulator family member A.	0.822
Chd4	CHD3	ENSSTOP00000006839	ENSSTOP00000015560	Uncharacterized protein.	Chromodomain helicase DNA binding protein 3.	0.999
Chd4	ENSSTOP00000026639	ENSSTOP00000006839	ENSSTOP00000026639	Uncharacterized protein.	Hist_deacetyl domain-containing protein.	0.997
Chd4	HDAC2	ENSSTOP00000006839	ENSSTOP00000011457	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
Chd4	Hdac1	ENSSTOP00000006839	ENSSTOP00000010833	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.998
Chd4	MTA1	ENSSTOP00000006839	ENSSTOP00000007254	Uncharacterized protein.	Metastasis associated 1.	0.999
Chd4	MTA2	ENSSTOP00000006839	ENSSTOP00000002588	Uncharacterized protein.	Metastasis associated 1 family member 2.	0.999
Chd4	RCOR1	ENSSTOP00000006839	ENSSTOP00000020809	Uncharacterized protein.	REST corepressor 1.	0.804
Chd4	SAP30	ENSSTOP00000006839	ENSSTOP00000019204	Uncharacterized protein.	Sin3A associated protein 30.	0.768
Chd4	SIN3A	ENSSTOP00000006839	ENSSTOP00000015334	Uncharacterized protein.	SIN3 transcription regulator family member A.	0.879
ENSSTOP00000026639	CHD3	ENSSTOP00000026639	ENSSTOP00000015560	Hist_deacetyl domain-containing protein.	Chromodomain helicase DNA binding protein 3.	0.992
ENSSTOP00000026639	Chd4	ENSSTOP00000026639	ENSSTOP00000006839	Hist_deacetyl domain-containing protein.	Uncharacterized protein.	0.997