ESPN protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ESPN

Espin. (872 aa)

Predicted Functional Partners:

MYO3B

0.974

MYO3A

0.929

WHRN

0.844

MYO15A

0.833

EPS8

0.803

EPS8L2

0.779

Myo15b

0.773

ENSSTOP00000031765

0.773

FSCN1

0.770

MYO7A

0.757

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSTOP00000031765	EPS8	ENSSTOP00000031765	ENSSTOP00000030686	Uncharacterized protein.	Epidermal growth factor receptor pathway substrate 8.	0.679
ENSSTOP00000031765	EPS8L2	ENSSTOP00000031765	ENSSTOP00000026698	Uncharacterized protein.	EPS8 like 2.	0.736
ENSSTOP00000031765	ESPN	ENSSTOP00000031765	ENSSTOP00000012230	Uncharacterized protein.	Espin.	0.773
ENSSTOP00000031765	FSCN1	ENSSTOP00000031765	ENSSTOP00000021848	Uncharacterized protein.	Fascin.	0.432
ENSSTOP00000031765	MYO3A	ENSSTOP00000031765	ENSSTOP00000024993	Uncharacterized protein.	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.592
ENSSTOP00000031765	MYO3B	ENSSTOP00000031765	ENSSTOP00000007186	Uncharacterized protein.	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.600
ENSSTOP00000031765	Myo15b	ENSSTOP00000031765	ENSSTOP00000016921	Uncharacterized protein.	SH3 domain-containing protein.	0.900
ENSSTOP00000031765	WHRN	ENSSTOP00000031765	ENSSTOP00000015942	Uncharacterized protein.	Whirlin.	0.948
EPS8	ENSSTOP00000031765	ENSSTOP00000030686	ENSSTOP00000031765	Epidermal growth factor receptor pathway substrate 8.	Uncharacterized protein.	0.679
EPS8	EPS8L2	ENSSTOP00000030686	ENSSTOP00000026698	Epidermal growth factor receptor pathway substrate 8.	EPS8 like 2.	0.656
EPS8	ESPN	ENSSTOP00000030686	ENSSTOP00000012230	Epidermal growth factor receptor pathway substrate 8.	Espin.	0.803
EPS8	MYO15A	ENSSTOP00000030686	ENSSTOP00000015919	Epidermal growth factor receptor pathway substrate 8.	Myosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.854
EPS8	MYO3A	ENSSTOP00000030686	ENSSTOP00000024993	Epidermal growth factor receptor pathway substrate 8.	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.836
EPS8	MYO3B	ENSSTOP00000030686	ENSSTOP00000007186	Epidermal growth factor receptor pathway substrate 8.	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.687
EPS8	MYO7A	ENSSTOP00000030686	ENSSTOP00000024404	Epidermal growth factor receptor pathway substrate 8.	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.469
EPS8	Myo15b	ENSSTOP00000030686	ENSSTOP00000016921	Epidermal growth factor receptor pathway substrate 8.	SH3 domain-containing protein.	0.679
EPS8	WHRN	ENSSTOP00000030686	ENSSTOP00000015942	Epidermal growth factor receptor pathway substrate 8.	Whirlin.	0.834
EPS8L2	ENSSTOP00000031765	ENSSTOP00000026698	ENSSTOP00000031765	EPS8 like 2.	Uncharacterized protein.	0.736
EPS8L2	EPS8	ENSSTOP00000026698	ENSSTOP00000030686	EPS8 like 2.	Epidermal growth factor receptor pathway substrate 8.	0.656
EPS8L2	ESPN	ENSSTOP00000026698	ENSSTOP00000012230	EPS8 like 2.	Espin.	0.779