node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRCC3 | Nlrp14 | ENSSTOP00000019166 | ENSSTOP00000012288 | BRCA1/BRCA2-containing complex subunit 3. | Uncharacterized protein. | 0.833 |
GSDMD | IL1B | ENSSTOP00000021754 | ENSSTOP00000002047 | Gasdermin D. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.862 |
GSDMD | Nlrp14 | ENSSTOP00000021754 | ENSSTOP00000012288 | Gasdermin D. | Uncharacterized protein. | 0.817 |
GSDMD | PYCARD | ENSSTOP00000021754 | ENSSTOP00000012013 | Gasdermin D. | PYD and CARD domain containing. | 0.632 |
IL1B | GSDMD | ENSSTOP00000002047 | ENSSTOP00000021754 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Gasdermin D. | 0.862 |
IL1B | NFKB1 | ENSSTOP00000002047 | ENSSTOP00000010277 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Nuclear factor kappa B subunit 1. | 0.939 |
IL1B | Nlrp14 | ENSSTOP00000002047 | ENSSTOP00000012288 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Uncharacterized protein. | 0.860 |
IL1B | PYCARD | ENSSTOP00000002047 | ENSSTOP00000012013 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | PYD and CARD domain containing. | 0.931 |
IL1B | RELA | ENSSTOP00000002047 | ENSSTOP00000017232 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | RELA proto-oncogene, NF-kB subunit. | 0.929 |
IL1B | TXNIP | ENSSTOP00000002047 | ENSSTOP00000012458 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Thioredoxin interacting protein. | 0.561 |
MAVS | NFKB1 | ENSSTOP00000013856 | ENSSTOP00000010277 | Mitochondrial antiviral signaling protein. | Nuclear factor kappa B subunit 1. | 0.586 |
MAVS | Nlrp14 | ENSSTOP00000013856 | ENSSTOP00000012288 | Mitochondrial antiviral signaling protein. | Uncharacterized protein. | 0.862 |
MAVS | RELA | ENSSTOP00000013856 | ENSSTOP00000017232 | Mitochondrial antiviral signaling protein. | RELA proto-oncogene, NF-kB subunit. | 0.415 |
NFKB1 | IL1B | ENSSTOP00000010277 | ENSSTOP00000002047 | Nuclear factor kappa B subunit 1. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.939 |
NFKB1 | MAVS | ENSSTOP00000010277 | ENSSTOP00000013856 | Nuclear factor kappa B subunit 1. | Mitochondrial antiviral signaling protein. | 0.586 |
NFKB1 | Nlrp14 | ENSSTOP00000010277 | ENSSTOP00000012288 | Nuclear factor kappa B subunit 1. | Uncharacterized protein. | 0.802 |
NFKB1 | RELA | ENSSTOP00000010277 | ENSSTOP00000017232 | Nuclear factor kappa B subunit 1. | RELA proto-oncogene, NF-kB subunit. | 0.999 |
Nlrp14 | BRCC3 | ENSSTOP00000012288 | ENSSTOP00000019166 | Uncharacterized protein. | BRCA1/BRCA2-containing complex subunit 3. | 0.833 |
Nlrp14 | GSDMD | ENSSTOP00000012288 | ENSSTOP00000021754 | Uncharacterized protein. | Gasdermin D. | 0.817 |
Nlrp14 | IL1B | ENSSTOP00000012288 | ENSSTOP00000002047 | Uncharacterized protein. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.860 |