node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSMA1 | PSMB4 | ENSSTOP00000005600 | ENSSTOP00000010808 | Proteasome subunit alpha type. | Proteasome subunit beta; Belongs to the peptidase T1B family. | 0.999 |
PSMA1 | PSMC2 | ENSSTOP00000005600 | ENSSTOP00000004673 | Proteasome subunit alpha type. | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. | 0.999 |
PSMA1 | PSMC3 | ENSSTOP00000005600 | ENSSTOP00000009906 | Proteasome subunit alpha type. | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. | 0.999 |
PSMA1 | PSMC4 | ENSSTOP00000005600 | ENSSTOP00000011204 | Proteasome subunit alpha type. | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. | 0.997 |
PSMA1 | PSMD1 | ENSSTOP00000005600 | ENSSTOP00000008396 | Proteasome subunit alpha type. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.998 |
PSMA1 | PSMD4 | ENSSTOP00000005600 | ENSSTOP00000000551 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 4. | 0.999 |
PSMA1 | PSMD6 | ENSSTOP00000005600 | ENSSTOP00000011269 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 6. | 0.999 |
PSMA1 | PSMD7 | ENSSTOP00000005600 | ENSSTOP00000011762 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 7. | 0.999 |
PSMA1 | Psmc6 | ENSSTOP00000005600 | ENSSTOP00000012983 | Proteasome subunit alpha type. | 26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 0.999 |
PSMA1 | USP14 | ENSSTOP00000005600 | ENSSTOP00000005775 | Proteasome subunit alpha type. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.993 |
PSMB4 | PSMA1 | ENSSTOP00000010808 | ENSSTOP00000005600 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome subunit alpha type. | 0.999 |
PSMB4 | PSMC2 | ENSSTOP00000010808 | ENSSTOP00000004673 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. | 0.998 |
PSMB4 | PSMC3 | ENSSTOP00000010808 | ENSSTOP00000009906 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. | 0.998 |
PSMB4 | PSMC4 | ENSSTOP00000010808 | ENSSTOP00000011204 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. | 0.998 |
PSMB4 | PSMD1 | ENSSTOP00000010808 | ENSSTOP00000008396 | Proteasome subunit beta; Belongs to the peptidase T1B family. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.995 |
PSMB4 | PSMD4 | ENSSTOP00000010808 | ENSSTOP00000000551 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 4. | 0.999 |
PSMB4 | PSMD6 | ENSSTOP00000010808 | ENSSTOP00000011269 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 6. | 0.999 |
PSMB4 | PSMD7 | ENSSTOP00000010808 | ENSSTOP00000011762 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 7. | 0.999 |
PSMB4 | Psmc6 | ENSSTOP00000010808 | ENSSTOP00000012983 | Proteasome subunit beta; Belongs to the peptidase T1B family. | 26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 0.999 |
PSMB4 | USP14 | ENSSTOP00000010808 | ENSSTOP00000005775 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.990 |