STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK1Calponin-homology (CH) domain-containing protein. (728 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
    
 
 0.834
SUN5
Sad1 and UNC84 domain containing 5.
    
 
 0.737
HOOK3
Hook microtubule tethering protein 3.
  
 
 
0.699
PLK4
Polo like kinase 4.
    
 0.665
PMFBP1
Polyamine modulated factor 1 binding protein 1.
      
 0.635
ESPL1
Extra spindle pole bodies like 1, separase.
    
 0.591
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 0.584
FAM160B1
Family with sequence similarity 160 member B1.
    
 0.576
FAM160A2
Family with sequence similarity 160 member A2.
    
 0.562
CEP135
Centrosomal protein 135.
    
 
 0.552
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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