STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mov10AAA_12 domain-containing protein. (1054 aa)    
Predicted Functional Partners:
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 0.710
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
    
 0.702
LOC101960725
Uncharacterized protein.
 
      0.699
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
   
 0.675
UPF1
UPF1 RNA helicase and ATPase.
    
 
0.672
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
    
 0.645
AGO1
Argonaute RISC component 1; Belongs to the argonaute family.
    
 0.642
I3M8U5_ICTTR
Piwi domain-containing protein.
    
 0.619
DDX4
DEAD-box helicase 4; Belongs to the DEAD box helicase family.
    
 0.605
Tdrd12
CS domain-containing protein.
    
 0.550
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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