STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZEB1Zinc finger E-box binding homeobox 1. (1123 aa)    
Predicted Functional Partners:
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.955
CTBP2
C-terminal binding protein 2.
   
 
 0.829
ENSSTOP00000026667
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.829
SMAD3
Mothers against decapentaplegic homolog.
    
 
 0.696
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
    
 
 0.661
EP300
E1A binding protein p300.
    
 
 0.647
SMAD2
Mothers against decapentaplegic homolog.
    
 
 0.627
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 
 0.602
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.600
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.597
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.