MECOM protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMKMT	MECOM	ENSSTOP00000007488	ENSSTOP00000031742	Calmodulin-lysine N-methyltransferase.	MDS1 and EVI1 complex locus.	0.913
CTBP1	CTBP2	ENSSTOP00000027774	ENSSTOP00000024377	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.998
CTBP1	ENSSTOP00000026639	ENSSTOP00000027774	ENSSTOP00000026639	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hist_deacetyl domain-containing protein.	0.993
CTBP1	ENSSTOP00000026667	ENSSTOP00000027774	ENSSTOP00000026667	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.998
CTBP1	HDAC2	ENSSTOP00000027774	ENSSTOP00000011457	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
CTBP1	Hdac1	ENSSTOP00000027774	ENSSTOP00000010833	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.993
CTBP1	MECOM	ENSSTOP00000027774	ENSSTOP00000031742	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	MDS1 and EVI1 complex locus.	0.997
CTBP2	CTBP1	ENSSTOP00000024377	ENSSTOP00000027774	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.998
CTBP2	ENSSTOP00000026639	ENSSTOP00000024377	ENSSTOP00000026639	C-terminal binding protein 2.	Hist_deacetyl domain-containing protein.	0.947
CTBP2	HDAC2	ENSSTOP00000024377	ENSSTOP00000011457	C-terminal binding protein 2.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.986
CTBP2	Hdac1	ENSSTOP00000024377	ENSSTOP00000010833	C-terminal binding protein 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.947
CTBP2	MECOM	ENSSTOP00000024377	ENSSTOP00000031742	C-terminal binding protein 2.	MDS1 and EVI1 complex locus.	0.975
ENSSTOP00000026639	CTBP1	ENSSTOP00000026639	ENSSTOP00000027774	Hist_deacetyl domain-containing protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.993
ENSSTOP00000026639	CTBP2	ENSSTOP00000026639	ENSSTOP00000024377	Hist_deacetyl domain-containing protein.	C-terminal binding protein 2.	0.947
ENSSTOP00000026639	ENSSTOP00000026667	ENSSTOP00000026639	ENSSTOP00000026667	Hist_deacetyl domain-containing protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.947
ENSSTOP00000026639	HDAC2	ENSSTOP00000026639	ENSSTOP00000011457	Hist_deacetyl domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
ENSSTOP00000026639	Hdac1	ENSSTOP00000026639	ENSSTOP00000010833	Hist_deacetyl domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.549
ENSSTOP00000026639	MECOM	ENSSTOP00000026639	ENSSTOP00000031742	Hist_deacetyl domain-containing protein.	MDS1 and EVI1 complex locus.	0.978
ENSSTOP00000026639	RBBP4	ENSSTOP00000026639	ENSSTOP00000010777	Hist_deacetyl domain-containing protein.	RB binding protein 4, chromatin remodeling factor.	0.968
ENSSTOP00000026639	RBBP7	ENSSTOP00000026639	ENSSTOP00000002520	Hist_deacetyl domain-containing protein.	RB binding protein 7, chromatin remodeling factor.	0.971