STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCL1MCL1 apoptosis regulator, BCL2 family member. (333 aa)    
Predicted Functional Partners:
BCL2L11
Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.
    
 0.999
BAX
BCL2 associated X, apoptosis regulator.
    
0.992
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.978
BAK1
BCL2 antagonist/killer 1.
    
0.973
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 
 0.946
TNKS2
Poly [ADP-ribose] polymerase.
    
 
 0.937
FBXW7
F-box and WD repeat domain containing 7.
    
 
 0.918
Becn1
Beclin 1.
    
 0.909
BAD
BCL2 associated agonist of cell death.
   
 0.866
BECN2
Beclin 2.
    
 0.863
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.