STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD4Mothers against decapentaplegic homolog. (552 aa)    
Predicted Functional Partners:
SMAD2
Mothers against decapentaplegic homolog.
   
0.999
SMAD3
Mothers against decapentaplegic homolog.
   
0.999
SMAD1
Mothers against decapentaplegic homolog.
   
0.996
SKI
SKI proto-oncogene.
    
 0.988
SKIL
SKI like proto-oncogene.
    
 0.987
SMAD9
Mothers against decapentaplegic homolog.
   
0.984
SMAD5
Mothers against decapentaplegic homolog.
   
0.984
USP9X
Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family.
    
 0.977
TRIM33
Tripartite motif containing 33.
   
 0.967
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.956
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.