STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGR1Interferon gamma receptor 1. (476 aa)    
Predicted Functional Partners:
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  
 
 0.996
IFNGR2
Interferon gamma receptor 2.
   
 0.993
STAT1
Signal transducer and activator of transcription.
   
 0.989
JAK2
Tyrosine-protein kinase.
   
 0.960
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.960
JAK1
Tyrosine-protein kinase.
   
 0.959
Ifnar2
Uncharacterized protein.
  
 
 0.944
TYK2
Tyrosine-protein kinase.
   
 0.933
JAK3
Tyrosine-protein kinase.
   
 0.933
LOC101968765
Uncharacterized protein.
  
 
 0.933
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (30%) [HD]