STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC1HIC ZBTB transcriptional repressor 1. (736 aa)    
Predicted Functional Partners:
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.725
SIRT1
Sirtuin 1.
    
 
 0.715
PIAS2
Protein inhibitor of activated STAT 2.
    
  0.604
Ube2i
SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5. Sumoylates p53/TP53 at 'Lys-386'; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.580
ENSSTOP00000025041
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.580
KCTD2
Potassium channel tetramerization domain containing 2.
    
  0.561
CTBP2
C-terminal binding protein 2.
    
 
 0.561
ENSSTOP00000026667
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.561
Mia2
Uncharacterized protein.
    
 0.558
ENSSTOP00000029812
Small ubiquitin-related modifier.
    
  0.533
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (12%) [HD]