MAX protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAX

MYC associated factor X. (160 aa)

Predicted Functional Partners:

MYC

0.999

MGA

0.989

MXD1

0.980

MXI1

0.972

MNT

0.955

MYCL

0.951

Mycn

0.947

LOC101955349

0.947

L3MBTL2

0.912

MAPK14

0.901

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L3MBTL2	MAX	ENSSTOP00000000214	ENSSTOP00000017509	L3MBTL histone methyl-lysine binding protein 2.	MYC associated factor X.	0.912
L3MBTL2	MGA	ENSSTOP00000000214	ENSSTOP00000031391	L3MBTL histone methyl-lysine binding protein 2.	MAX dimerization protein MGA.	0.933
L3MBTL2	MNT	ENSSTOP00000000214	ENSSTOP00000021961	L3MBTL histone methyl-lysine binding protein 2.	MAX network transcriptional repressor.	0.522
L3MBTL2	MXD1	ENSSTOP00000000214	ENSSTOP00000000641	L3MBTL histone methyl-lysine binding protein 2.	MAX dimerization protein 1.	0.459
L3MBTL2	MXI1	ENSSTOP00000000214	ENSSTOP00000018573	L3MBTL histone methyl-lysine binding protein 2.	MAX interactor 1, dimerization protein.	0.483
L3MBTL2	MYC	ENSSTOP00000000214	ENSSTOP00000004430	L3MBTL histone methyl-lysine binding protein 2.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.425
L3MBTL2	MYCL	ENSSTOP00000000214	ENSSTOP00000004508	L3MBTL histone methyl-lysine binding protein 2.	MYCL proto-oncogene, bHLH transcription factor.	0.542
LOC101955349	MAX	ENSSTOP00000019773	ENSSTOP00000017509	BHLH domain-containing protein.	MYC associated factor X.	0.947
LOC101955349	MNT	ENSSTOP00000019773	ENSSTOP00000021961	BHLH domain-containing protein.	MAX network transcriptional repressor.	0.694
LOC101955349	MXD1	ENSSTOP00000019773	ENSSTOP00000000641	BHLH domain-containing protein.	MAX dimerization protein 1.	0.642
LOC101955349	MXI1	ENSSTOP00000019773	ENSSTOP00000018573	BHLH domain-containing protein.	MAX interactor 1, dimerization protein.	0.664
LOC101955349	MYC	ENSSTOP00000019773	ENSSTOP00000004430	BHLH domain-containing protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.684
LOC101955349	MYCL	ENSSTOP00000019773	ENSSTOP00000004508	BHLH domain-containing protein.	MYCL proto-oncogene, bHLH transcription factor.	0.643
MAPK14	MAX	ENSSTOP00000023055	ENSSTOP00000017509	Mitogen-activated protein kinase.	MYC associated factor X.	0.901
MAPK14	MYC	ENSSTOP00000023055	ENSSTOP00000004430	Mitogen-activated protein kinase.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.748
MAPK14	MYCL	ENSSTOP00000023055	ENSSTOP00000004508	Mitogen-activated protein kinase.	MYCL proto-oncogene, bHLH transcription factor.	0.607
MAX	L3MBTL2	ENSSTOP00000017509	ENSSTOP00000000214	MYC associated factor X.	L3MBTL histone methyl-lysine binding protein 2.	0.912
MAX	LOC101955349	ENSSTOP00000017509	ENSSTOP00000019773	MYC associated factor X.	BHLH domain-containing protein.	0.947
MAX	MAPK14	ENSSTOP00000017509	ENSSTOP00000023055	MYC associated factor X.	Mitogen-activated protein kinase.	0.901
MAX	MGA	ENSSTOP00000017509	ENSSTOP00000031391	MYC associated factor X.	MAX dimerization protein MGA.	0.989