STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.995
STIP1
Stress induced phosphoprotein 1.
  
 0.937
HSPA4
Heat shock protein family A (Hsp70) member 4.
  
0.928
DNAJC2
DnaJ heat shock protein family (Hsp40) member C2.
   
 0.916
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
 
 0.899
NR3C1
Nuclear receptor subfamily 3 group C member 1.
    
 0.897
DNAJA2
DnaJ heat shock protein family (Hsp40) member A2.
 
 0.890
Hspa5
Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]
  
0.883
TLR2
Toll like receptor 2; Belongs to the Toll-like receptor family.
    
 0.880
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1.
 
 0.876
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.