DLX2 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DLX2

Distal-less homeobox 2. (329 aa)

Predicted Functional Partners:

DLX1

0.833

DLX6

0.812

TBR1

0.631

IRX1

0.602

MEIS2

0.576

IRX2

0.575

IRX5

0.572

RUNX2

0.543

LEF1

0.539

FOXG1

0.497

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLX1	DLX2	ENSSTOP00000011616	ENSSTOP00000018531	Distal-less homeobox 1.	Distal-less homeobox 2.	0.833
DLX1	FOXG1	ENSSTOP00000011616	ENSSTOP00000018836	Distal-less homeobox 1.	Forkhead box G1.	0.404
DLX1	IRX1	ENSSTOP00000011616	ENSSTOP00000032287	Distal-less homeobox 1.	Iroquois homeobox 1.	0.483
DLX1	IRX2	ENSSTOP00000011616	ENSSTOP00000003160	Distal-less homeobox 1.	Iroquois homeobox 2.	0.498
DLX1	IRX5	ENSSTOP00000011616	ENSSTOP00000015790	Distal-less homeobox 1.	Iroquois homeobox 5.	0.498
DLX1	LEF1	ENSSTOP00000011616	ENSSTOP00000032586	Distal-less homeobox 1.	Lymphoid enhancer binding factor 1.	0.617
DLX1	MEIS2	ENSSTOP00000011616	ENSSTOP00000025999	Distal-less homeobox 1.	Meis homeobox 2.	0.491
DLX1	RUNX2	ENSSTOP00000011616	ENSSTOP00000029414	Distal-less homeobox 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.440
DLX2	DLX1	ENSSTOP00000018531	ENSSTOP00000011616	Distal-less homeobox 2.	Distal-less homeobox 1.	0.833
DLX2	DLX6	ENSSTOP00000018531	ENSSTOP00000015333	Distal-less homeobox 2.	Distal-less homeobox 6.	0.812
DLX2	FOXG1	ENSSTOP00000018531	ENSSTOP00000018836	Distal-less homeobox 2.	Forkhead box G1.	0.497
DLX2	IRX1	ENSSTOP00000018531	ENSSTOP00000032287	Distal-less homeobox 2.	Iroquois homeobox 1.	0.602
DLX2	IRX2	ENSSTOP00000018531	ENSSTOP00000003160	Distal-less homeobox 2.	Iroquois homeobox 2.	0.575
DLX2	IRX5	ENSSTOP00000018531	ENSSTOP00000015790	Distal-less homeobox 2.	Iroquois homeobox 5.	0.572
DLX2	LEF1	ENSSTOP00000018531	ENSSTOP00000032586	Distal-less homeobox 2.	Lymphoid enhancer binding factor 1.	0.539
DLX2	MEIS2	ENSSTOP00000018531	ENSSTOP00000025999	Distal-less homeobox 2.	Meis homeobox 2.	0.576
DLX2	RUNX2	ENSSTOP00000018531	ENSSTOP00000029414	Distal-less homeobox 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.543
DLX2	TBR1	ENSSTOP00000018531	ENSSTOP00000021694	Distal-less homeobox 2.	T-box brain transcription factor 1.	0.631
DLX6	DLX2	ENSSTOP00000015333	ENSSTOP00000018531	Distal-less homeobox 6.	Distal-less homeobox 2.	0.812
DLX6	FOXG1	ENSSTOP00000015333	ENSSTOP00000018836	Distal-less homeobox 6.	Forkhead box G1.	0.513