| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | CAD | ENSSTOP00000007111 | ENSSTOP00000010164 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.838 |
| ALDH18A1 | GAD1 | ENSSTOP00000007111 | ENSSTOP00000003008 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate decarboxylase 1. | 0.941 |
| ALDH18A1 | GAD2 | ENSSTOP00000007111 | ENSSTOP00000001835 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate decarboxylase 2. | 0.941 |
| ALDH18A1 | GLS | ENSSTOP00000007111 | ENSSTOP00000018623 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutaminase. | 0.942 |
| ALDH18A1 | GLS2 | ENSSTOP00000007111 | ENSSTOP00000031755 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutaminase 2. | 0.942 |
| ALDH18A1 | GLUL | ENSSTOP00000007111 | ENSSTOP00000013014 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamine synthetase. | 0.969 |
| ALDH18A1 | Glud1 | ENSSTOP00000007111 | ENSSTOP00000011510 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.972 |
| CAD | ALDH18A1 | ENSSTOP00000010164 | ENSSTOP00000007111 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.838 |
| CAD | GAD1 | ENSSTOP00000010164 | ENSSTOP00000003008 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamate decarboxylase 1. | 0.934 |
| CAD | GAD2 | ENSSTOP00000010164 | ENSSTOP00000001835 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamate decarboxylase 2. | 0.934 |
| CAD | GLS | ENSSTOP00000010164 | ENSSTOP00000018623 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutaminase. | 0.962 |
| CAD | GLS2 | ENSSTOP00000010164 | ENSSTOP00000031755 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutaminase 2. | 0.929 |
| CAD | GLUL | ENSSTOP00000010164 | ENSSTOP00000013014 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine synthetase. | 0.949 |
| CAD | Glud1 | ENSSTOP00000010164 | ENSSTOP00000011510 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.905 |
| CAD | I3MJ47_ICTTR | ENSSTOP00000010164 | ENSSTOP00000011134 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Uncharacterized protein. | 0.494 |
| CAD | SIRT5 | ENSSTOP00000010164 | ENSSTOP00000012285 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.820 |
| GAD1 | ALDH18A1 | ENSSTOP00000003008 | ENSSTOP00000007111 | Glutamate decarboxylase 1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.941 |
| GAD1 | CAD | ENSSTOP00000003008 | ENSSTOP00000010164 | Glutamate decarboxylase 1. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.934 |
| GAD1 | GAD2 | ENSSTOP00000003008 | ENSSTOP00000001835 | Glutamate decarboxylase 1. | Glutamate decarboxylase 2. | 0.996 |
| GAD1 | GLS | ENSSTOP00000003008 | ENSSTOP00000018623 | Glutamate decarboxylase 1. | Glutaminase. | 0.943 |
