STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD276CD276 molecule. (316 aa)    
Predicted Functional Partners:
CD28
CD28 molecule.
     
 0.751
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
     
 0.749
TREML2
Triggering receptor expressed on myeloid cells like 2.
   
  
 0.610
Cd86
Ig-like domain-containing protein.
      
 0.608
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
      
 0.579
TNFRSF9
TNF receptor superfamily member 9.
      
 0.571
VTCN1
V-set domain containing T cell activation inhibitor 1.
     
0.558
CD4
CD4 molecule.
    
 
 0.541
ICOS
Inducible T cell costimulator.
      
 0.539
CD8A
CD8a molecule.
      
 0.491
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.