STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (265 aa)    
Predicted Functional Partners:
MAOA
Amine oxidase.
    
 0.933
MAOB
Amine oxidase.
    
 0.933
CYP1A1
Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.921
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.920
DDC
Dopa decarboxylase.
  
 
 0.908
DBH
Dopamine beta-hydroxylase.
     
 0.908
PNMT
Phenylethanolamine N-methyltransferase.
     
 0.885
ALDH3A1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.867
ALDH3B1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.857
ADH7
Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide.
    
 0.856
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.