| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | CHEK1 | ENSSTOP00000004029 | ENSSTOP00000002203 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | 0.996 |
| ATM | DAXX | ENSSTOP00000004029 | ENSSTOP00000002184 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Death domain associated protein. | 0.455 |
| ATM | EP300 | ENSSTOP00000004029 | ENSSTOP00000000650 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | E1A binding protein p300. | 0.410 |
| ATM | HIPK2 | ENSSTOP00000004029 | ENSSTOP00000005333 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Homeodomain interacting protein kinase 2. | 0.604 |
| ATM | Mdm4 | ENSSTOP00000004029 | ENSSTOP00000003760 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. | 0.990 |
| ATM | TP53 | ENSSTOP00000004029 | ENSSTOP00000019678 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| CHEK1 | ATM | ENSSTOP00000002203 | ENSSTOP00000004029 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.996 |
| CHEK1 | Mdm4 | ENSSTOP00000002203 | ENSSTOP00000003760 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. | 0.832 |
| CHEK1 | TP53 | ENSSTOP00000002203 | ENSSTOP00000019678 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| CREBBP | DAXX | ENSSTOP00000004511 | ENSSTOP00000002184 | CREB binding protein. | Death domain associated protein. | 0.935 |
| CREBBP | EP300 | ENSSTOP00000004511 | ENSSTOP00000000650 | CREB binding protein. | E1A binding protein p300. | 0.999 |
| CREBBP | HIPK2 | ENSSTOP00000004511 | ENSSTOP00000005333 | CREB binding protein. | Homeodomain interacting protein kinase 2. | 0.710 |
| CREBBP | Mdm4 | ENSSTOP00000004511 | ENSSTOP00000003760 | CREB binding protein. | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. | 0.613 |
| CREBBP | TADA3 | ENSSTOP00000004511 | ENSSTOP00000001874 | CREB binding protein. | Transcriptional adaptor 3. | 0.593 |
| CREBBP | TP53 | ENSSTOP00000004511 | ENSSTOP00000019678 | CREB binding protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| DAXX | ATM | ENSSTOP00000002184 | ENSSTOP00000004029 | Death domain associated protein. | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.455 |
| DAXX | CREBBP | ENSSTOP00000002184 | ENSSTOP00000004511 | Death domain associated protein. | CREB binding protein. | 0.935 |
| DAXX | EP300 | ENSSTOP00000002184 | ENSSTOP00000000650 | Death domain associated protein. | E1A binding protein p300. | 0.805 |
| DAXX | HIPK2 | ENSSTOP00000002184 | ENSSTOP00000005333 | Death domain associated protein. | Homeodomain interacting protein kinase 2. | 0.984 |
| DAXX | Mdm4 | ENSSTOP00000002184 | ENSSTOP00000003760 | Death domain associated protein. | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. | 0.911 |
