STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RhocUncharacterized protein. (193 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.998
ITSN1
Intersectin 1.
    
 0.979
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
  
 0.942
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.935
ARHGAP35
Rho GTPase activating protein 35.
    
 0.933
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.933
PKN1
Protein kinase N1.
    
 0.932
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
 0.924
Akap13
Uncharacterized protein.
   
 0.920
ARHGAP1
Rho GTPase activating protein 1.
    
 0.909
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.