STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF5Rho guanine nucleotide exchange factor 5. (1570 aa)    
Predicted Functional Partners:
RHOG
Ras homolog family member G.
    
 0.706
EPHA8
EPH receptor A8.
    
 0.703
EPHB6
EPH receptor B6.
    
 0.699
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.668
EPHA1
EPH receptor A1.
    
 0.642
EPHA2
EPH receptor A2.
    
 0.622
Rhoa
Ras homolog family member A.
    
 0.596
LOC101959358
Uncharacterized protein.
    
 0.596
Rhoc
Uncharacterized protein.
    
 0.596
ENSSTOP00000031001
Uncharacterized protein.
    
 0.596
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.