SIX2 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SIX2

SIX homeobox 2. (296 aa)

Predicted Functional Partners:

EYA1

0.850

EYA2

0.778

EYA3

0.718

EYA4

0.684

SALL1

0.471

PAX2

0.437

CITED1

0.414

WT1

0.408

WNT9B

0.407

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CITED1	SIX2	ENSSTOP00000007553	ENSSTOP00000020637	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	SIX homeobox 2.	0.414
EYA1	EYA2	ENSSTOP00000004692	ENSSTOP00000004351	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.560
EYA1	EYA3	ENSSTOP00000004692	ENSSTOP00000030612	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.564
EYA1	EYA4	ENSSTOP00000004692	ENSSTOP00000025893	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.574
EYA1	PAX2	ENSSTOP00000004692	ENSSTOP00000010388	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Paired box 2.	0.476
EYA1	SALL1	ENSSTOP00000004692	ENSSTOP00000022904	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Spalt like transcription factor 1.	0.449
EYA1	SIX2	ENSSTOP00000004692	ENSSTOP00000020637	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.850
EYA2	EYA1	ENSSTOP00000004351	ENSSTOP00000004692	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.560
EYA2	EYA3	ENSSTOP00000004351	ENSSTOP00000030612	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.663
EYA2	EYA4	ENSSTOP00000004351	ENSSTOP00000025893	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.563
EYA2	SIX2	ENSSTOP00000004351	ENSSTOP00000020637	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.778
EYA3	EYA1	ENSSTOP00000030612	ENSSTOP00000004692	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.564
EYA3	EYA2	ENSSTOP00000030612	ENSSTOP00000004351	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.663
EYA3	EYA4	ENSSTOP00000030612	ENSSTOP00000025893	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.563
EYA3	SIX2	ENSSTOP00000030612	ENSSTOP00000020637	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.718
EYA4	EYA1	ENSSTOP00000025893	ENSSTOP00000004692	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.574
EYA4	EYA2	ENSSTOP00000025893	ENSSTOP00000004351	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.563
EYA4	EYA3	ENSSTOP00000025893	ENSSTOP00000030612	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.563
EYA4	SIX2	ENSSTOP00000025893	ENSSTOP00000020637	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.684
PAX2	EYA1	ENSSTOP00000010388	ENSSTOP00000004692	Paired box 2.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.476