STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmed7GOLD domain-containing protein. (225 aa)    
Predicted Functional Partners:
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 0.984
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
 0.983
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.981
IRF3
Interferon regulatory factor 3.
    
 0.968
TMED2
Transmembrane p24 trafficking protein 2.
   
0.968
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.933
Tmed10
GOLD domain-containing protein.
   
0.912
LOC101963008
GOLD domain-containing protein.
   
 0.912
TICAM2
Toll like receptor adaptor molecule 2.
 
    
 0.906
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.899
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.