STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES6Hes family bHLH transcription factor 6. (224 aa)    
Predicted Functional Partners:
HES3
Hes family bHLH transcription factor 3.
     
 0.905
HES1
Hes family bHLH transcription factor 1.
    
0.899
HES7
Hes family bHLH transcription factor 7.
    
0.892
HES2
Hes family bHLH transcription factor 2.
    
0.855
FANCG
FA complementation group G.
    
  0.673
FANCL
FA complementation group L.
    
  0.673
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
  0.673
HES5
Hes family bHLH transcription factor 5.
    
 0.639
TLE1
TLE family member 1, transcriptional corepressor.
    
 
 0.627
FANCE
FA complementation group E.
    
  0.566
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.