STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3NCB9_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (277 aa)    
Predicted Functional Partners:
MST1R
Macrophage stimulating 1 receptor.
    
  0.768
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.768
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.641
WDR90
WD repeat domain 90.
    
 
 0.566
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
    
 0.511
Pinlyp
Uncharacterized protein.
    
  0.497
SNED1
Sushi, nidogen and EGF like domains 1.
    
  0.491
TFPI
Tissue factor pathway inhibitor.
    
 0.482
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
    
 0.479
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
    
  0.460
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.