FGA protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

FGA

Fibrinogen alpha chain. (788 aa)

Predicted Functional Partners:

FGG

0.999

F2

0.999

FGB

0.999

PLG

0.976

SERPINC1

0.973

AHSG

0.964

Itgb3

0.909

SERPINF2

0.898

SERPIND1

0.884

HRG

0.881

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSG	F2	ENSSTOP00000008482	ENSSTOP00000004608	Alpha 2-HS glycoprotein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.958
AHSG	FGA	ENSSTOP00000008482	ENSSTOP00000022246	Alpha 2-HS glycoprotein.	Fibrinogen alpha chain.	0.964
AHSG	FGB	ENSSTOP00000008482	ENSSTOP00000009108	Alpha 2-HS glycoprotein.	Fibrinogen beta chain.	0.910
AHSG	FGG	ENSSTOP00000008482	ENSSTOP00000000196	Alpha 2-HS glycoprotein.	Fibrinogen gamma chain.	0.932
AHSG	HRG	ENSSTOP00000008482	ENSSTOP00000011278	Alpha 2-HS glycoprotein.	Histidine rich glycoprotein.	0.779
AHSG	PLG	ENSSTOP00000008482	ENSSTOP00000023249	Alpha 2-HS glycoprotein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.953
AHSG	SERPINC1	ENSSTOP00000008482	ENSSTOP00000014347	Alpha 2-HS glycoprotein.	Serpin family C member 1; Belongs to the serpin family.	0.854
AHSG	SERPIND1	ENSSTOP00000008482	ENSSTOP00000013426	Alpha 2-HS glycoprotein.	Serpin family D member 1; Belongs to the serpin family.	0.629
AHSG	SERPINF2	ENSSTOP00000008482	ENSSTOP00000004693	Alpha 2-HS glycoprotein.	Serpin family F member 2; Belongs to the serpin family.	0.597
F2	AHSG	ENSSTOP00000004608	ENSSTOP00000008482	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Alpha 2-HS glycoprotein.	0.958
F2	FGA	ENSSTOP00000004608	ENSSTOP00000022246	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen alpha chain.	0.999
F2	FGB	ENSSTOP00000004608	ENSSTOP00000009108	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen beta chain.	0.998
F2	FGG	ENSSTOP00000004608	ENSSTOP00000000196	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen gamma chain.	0.998
F2	HRG	ENSSTOP00000004608	ENSSTOP00000011278	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Histidine rich glycoprotein.	0.766
F2	Itgb3	ENSSTOP00000004608	ENSSTOP00000002538	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Integrin beta; Belongs to the integrin beta chain family.	0.431
F2	PLG	ENSSTOP00000004608	ENSSTOP00000023249	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.945
F2	SERPINC1	ENSSTOP00000004608	ENSSTOP00000014347	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.999
F2	SERPIND1	ENSSTOP00000004608	ENSSTOP00000013426	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family D member 1; Belongs to the serpin family.	0.998
F2	SERPINF2	ENSSTOP00000004608	ENSSTOP00000004693	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family F member 2; Belongs to the serpin family.	0.877
FGA	AHSG	ENSSTOP00000022246	ENSSTOP00000008482	Fibrinogen alpha chain.	Alpha 2-HS glycoprotein.	0.964