STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL4RInterleukin 4 receptor. (795 aa)    
Predicted Functional Partners:
IL13RA1
Interleukin 13 receptor subunit alpha 1.
  
 
 0.996
IL13
Interleukin 13.
    
 0.995
Il2rg
Fibronectin type-III domain-containing protein.
    
 0.995
STAT6
Signal transducer and activator of transcription.
   
 0.974
JAK1
Tyrosine-protein kinase.
    
 0.957
IL13RA2
Interleukin 13 receptor subunit alpha 2.
    
 0.945
JAK3
Tyrosine-protein kinase.
    
 0.928
IL9
Interleukin 9.
  
  
 0.916
TYK2
Tyrosine-protein kinase.
    
 0.915
IL10
Interleukin 10.
     
 0.915
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.