STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMAGasdermin A. (421 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
   
 0.693
IL23A
Interleukin 23 subunit alpha.
  
     0.492
KRT25
Keratin 25; Belongs to the intermediate filament family.
  
   
 0.458
CASP14
Caspase 14; Belongs to the peptidase C14A family.
  
  
 0.456
Ffar3
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.446
PSORS1C2
Psoriasis susceptibility 1 candidate 2.
      
 0.439
AKAP3
A-kinase anchoring protein 3.
  
     0.433
TGM5
Transglutaminase 5.
      
 0.432
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
 
    
 0.412
BIRC7
Baculoviral IAP repeat containing 7.
      
 0.412
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.