node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNR1 | DRD2 | ENSSTOP00000022582 | ENSSTOP00000003194 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | 0.935 |
CNR1 | GNAI1 | ENSSTOP00000022582 | ENSSTOP00000010973 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i1. | 0.929 |
CNR1 | GNAI2 | ENSSTOP00000022582 | ENSSTOP00000014501 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i2. | 0.960 |
CNR1 | GNAI3 | ENSSTOP00000022582 | ENSSTOP00000007797 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i3. | 0.926 |
CNR1 | GNB1 | ENSSTOP00000022582 | ENSSTOP00000009443 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit beta 1. | 0.924 |
CNR1 | GNB2 | ENSSTOP00000022582 | ENSSTOP00000015043 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit beta 2. | 0.893 |
CNR1 | GNB4 | ENSSTOP00000022582 | ENSSTOP00000004669 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit beta 4. | 0.923 |
CNR1 | GNG2 | ENSSTOP00000022582 | ENSSTOP00000015121 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.911 |
CNR1 | GNG4 | ENSSTOP00000022582 | ENSSTOP00000014066 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.893 |
CNR1 | Gnao1 | ENSSTOP00000022582 | ENSSTOP00000006926 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha o1. | 0.908 |
DRD2 | CNR1 | ENSSTOP00000003194 | ENSSTOP00000022582 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.935 |
DRD2 | GNAI1 | ENSSTOP00000003194 | ENSSTOP00000010973 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i1. | 0.975 |
DRD2 | GNAI2 | ENSSTOP00000003194 | ENSSTOP00000014501 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i2. | 0.977 |
DRD2 | GNAI3 | ENSSTOP00000003194 | ENSSTOP00000007797 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i3. | 0.974 |
DRD2 | GNB1 | ENSSTOP00000003194 | ENSSTOP00000009443 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit beta 1. | 0.968 |
DRD2 | GNB2 | ENSSTOP00000003194 | ENSSTOP00000015043 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit beta 2. | 0.962 |
DRD2 | GNB4 | ENSSTOP00000003194 | ENSSTOP00000004669 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit beta 4. | 0.966 |
DRD2 | GNG2 | ENSSTOP00000003194 | ENSSTOP00000015121 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.962 |
DRD2 | GNG4 | ENSSTOP00000003194 | ENSSTOP00000014066 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.943 |
DRD2 | Gnao1 | ENSSTOP00000003194 | ENSSTOP00000006926 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha o1. | 0.980 |