STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM7ALysine demethylase 7A. (898 aa)    
Predicted Functional Partners:
LOC101967492
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.764
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.764
ARID5B
AT-rich interaction domain 5B.
     
 0.695
KDM6B
Lysine demethylase 6B.
   
 0.685
TOPBP1
DNA topoisomerase II binding protein 1.
    
   0.644
LOC106145260
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.640
LOC106145261
Histone H4.
    
 0.640
LOC101978127
Histone H4.
    
 0.640
LOC106145262
Histone H4.
    
 0.640
LOC101967236
Histone H4.
    
 0.640
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.