| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTRC | FBXW11 | ENSSTOP00000021235 | ENSSTOP00000022482 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box and WD repeat domain containing 11. | 0.999 |
| BTRC | GLI1 | ENSSTOP00000021235 | ENSSTOP00000019795 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | GLI family zinc finger 1. | 0.993 |
| BTRC | GLI3 | ENSSTOP00000021235 | ENSSTOP00000023186 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | GLI family zinc finger 3. | 0.994 |
| BTRC | SUFU | ENSSTOP00000021235 | ENSSTOP00000022235 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.636 |
| FBXW11 | BTRC | ENSSTOP00000022482 | ENSSTOP00000021235 | F-box and WD repeat domain containing 11. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.999 |
| FBXW11 | GLI1 | ENSSTOP00000022482 | ENSSTOP00000019795 | F-box and WD repeat domain containing 11. | GLI family zinc finger 1. | 0.964 |
| FBXW11 | GLI3 | ENSSTOP00000022482 | ENSSTOP00000023186 | F-box and WD repeat domain containing 11. | GLI family zinc finger 3. | 0.967 |
| FBXW11 | SUFU | ENSSTOP00000022482 | ENSSTOP00000022235 | F-box and WD repeat domain containing 11. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.625 |
| GLI1 | BTRC | ENSSTOP00000019795 | ENSSTOP00000021235 | GLI family zinc finger 1. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.993 |
| GLI1 | FBXW11 | ENSSTOP00000019795 | ENSSTOP00000022482 | GLI family zinc finger 1. | F-box and WD repeat domain containing 11. | 0.964 |
| GLI1 | GLI3 | ENSSTOP00000019795 | ENSSTOP00000023186 | GLI family zinc finger 1. | GLI family zinc finger 3. | 0.968 |
| GLI1 | KIF27 | ENSSTOP00000019795 | ENSSTOP00000012087 | GLI family zinc finger 1. | Kinesin family member 27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.957 |
| GLI1 | KIF7 | ENSSTOP00000019795 | ENSSTOP00000017647 | GLI family zinc finger 1. | Kinesin family member 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.962 |
| GLI1 | PTCH1 | ENSSTOP00000019795 | ENSSTOP00000031262 | GLI family zinc finger 1. | Patched 1. | 0.954 |
| GLI1 | SPOP | ENSSTOP00000019795 | ENSSTOP00000007024 | GLI family zinc finger 1. | Speckle type BTB/POZ protein. | 0.972 |
| GLI1 | SPOPL | ENSSTOP00000019795 | ENSSTOP00000017085 | GLI family zinc finger 1. | Speckle type BTB/POZ protein like. | 0.972 |
| GLI1 | STK36 | ENSSTOP00000019795 | ENSSTOP00000005842 | GLI family zinc finger 1. | Serine/threonine kinase 36. | 0.992 |
| GLI1 | SUFU | ENSSTOP00000019795 | ENSSTOP00000022235 | GLI family zinc finger 1. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.999 |
| GLI3 | BTRC | ENSSTOP00000023186 | ENSSTOP00000021235 | GLI family zinc finger 3. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.994 |
| GLI3 | FBXW11 | ENSSTOP00000023186 | ENSSTOP00000022482 | GLI family zinc finger 3. | F-box and WD repeat domain containing 11. | 0.967 |
