STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD50Ankyrin repeat domain 50. (1411 aa)    
Predicted Functional Partners:
PPP6C
Serine/threonine-protein phosphatase.
   
 0.749
PPP6R2
Protein phosphatase 6 regulatory subunit 2.
    
 0.677
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
    
 0.677
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
    
 0.677
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.625
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.614
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.614
IFT81
Intraflagellar transport 81.
    
 0.606
NEDD8
NEDD8 ubiquitin like modifier.
    
  0.603
Rps3
KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.
    
 0.602
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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