STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem43Transmembrane protein 43. (329 aa)    
Predicted Functional Partners:
NCLN
Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
      
 0.592
PKP2
Plakophilin 2.
      
 0.585
SMPD4
Sphingomyelin phosphodiesterase 4.
      
 0.573
JUP
Junction plakoglobin.
      
 0.571
DSG2
Desmoglein 2.
      
 0.569
EMD
Emerin.
    
 
 0.562
SUN2
Sad1 and UNC84 domain containing 2.
    
 
 0.546
Kbtbd12
Uncharacterized protein.
      
 0.532
STT3B
STT3 oligosaccharyltransferase complex catalytic subunit B.
      
 0.530
KCNG3
Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family.
      
 0.505
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.