STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1849 aa)    
Predicted Functional Partners:
ELMO1
Engulfment and cell motility 1.
    
 0.985
CRK
CRK proto-oncogene, adaptor protein.
    
 0.979
ELMO2
Engulfment and cell motility 2.
    
 0.975
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.966
RAC1
Rac family small GTPase 1.
   
 0.965
ELMO3
Engulfment and cell motility 3.
    
 0.962
RAC2
Rac family small GTPase 2.
   
 0.960
RAC3
Rac family small GTPase 3.
   
 0.957
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.942
RHOG
Ras homolog family member G.
   
 0.942
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.