STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKCRK proto-oncogene, adaptor protein. (305 aa)    
Predicted Functional Partners:
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.995
CBL
Cbl proto-oncogene.
    
 0.995
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.993
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.985
EGFR
Receptor protein-tyrosine kinase.
    
 0.983
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.983
MST1R
Macrophage stimulating 1 receptor.
   
 0.982
CBLB
Cbl proto-oncogene B.
    
 0.982
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.979
ABL2
Tyrosine-protein kinase.
    
0.978
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.