STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USF1Upstream transcription factor 1. (310 aa)    
Predicted Functional Partners:
USF2
Upstream transcription factor 2, c-fos interacting.
  
 
0.992
EP300
E1A binding protein p300.
    
 0.859
SP1
Sp1 transcription factor.
    
 0.849
CREBBP
CREB binding protein.
    
 0.786
GTF2I
General transcription factor IIi.
    
 
 0.779
TYR
Tyrosinase.
    
 
 0.646
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.646
ESR2
Estrogen receptor 2.
    
 0.609
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12.
   
   0.603
OCA2
OCA2 melanosomal transmembrane protein.
      
 0.598
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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