STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (523 aa)    
Predicted Functional Partners:
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
 
  
 
 0.926
NDOR1
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
 
  
 
 0.913
CYP2E1
Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.
  
0.897
CYP2U1
Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.
  
0.893
PLA2G3
Phospholipase A2 group III.
    
 0.889
LOC101976375
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.887
LOC101958990
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.885
ALOX5
Arachidonate 5-lipoxygenase.
    
 0.867
ALOX15
Arachidonate 15-lipoxygenase.
    
 0.862
LOC101978105
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.861
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.