node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM114A1 | RFC1 | ENSSTOP00000001048 | ENSSTOP00000006348 | Family with sequence similarity 114 member A1. | Replication factor C subunit 1. | 0.463 |
FAM114A1 | SMIM14 | ENSSTOP00000001048 | ENSSTOP00000025321 | Family with sequence similarity 114 member A1. | Small integral membrane protein 14. | 0.451 |
FAM114A1 | TMEM156 | ENSSTOP00000001048 | ENSSTOP00000025780 | Family with sequence similarity 114 member A1. | Transmembrane protein 156. | 0.575 |
IFNG | IL12B | ENSSTOP00000013397 | ENSSTOP00000004480 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | 0.685 |
IFNG | IL18BP | ENSSTOP00000013397 | ENSSTOP00000024965 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 18 binding protein. | 0.484 |
IFNG | TMEM156 | ENSSTOP00000013397 | ENSSTOP00000025780 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Transmembrane protein 156. | 0.446 |
IL12B | IFNG | ENSSTOP00000004480 | ENSSTOP00000013397 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.685 |
IL12B | TMEM156 | ENSSTOP00000004480 | ENSSTOP00000025780 | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. | Transmembrane protein 156. | 0.433 |
IL18BP | IFNG | ENSSTOP00000024965 | ENSSTOP00000013397 | Interleukin 18 binding protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.484 |
IL18BP | TMEM156 | ENSSTOP00000024965 | ENSSTOP00000025780 | Interleukin 18 binding protein. | Transmembrane protein 156. | 0.474 |
LIAS | N4BP2 | ENSSTOP00000001857 | ENSSTOP00000015390 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | NEDD4 binding protein 2. | 0.436 |
LIAS | PDS5A | ENSSTOP00000001857 | ENSSTOP00000011170 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | PDS5 cohesin associated factor A. | 0.447 |
LIAS | RFC1 | ENSSTOP00000001857 | ENSSTOP00000006348 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Replication factor C subunit 1. | 0.471 |
LIAS | SMIM14 | ENSSTOP00000001857 | ENSSTOP00000025321 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Small integral membrane protein 14. | 0.576 |
LIAS | TMEM156 | ENSSTOP00000001857 | ENSSTOP00000025780 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Transmembrane protein 156. | 0.448 |
LRRC66 | TMEM156 | ENSSTOP00000023806 | ENSSTOP00000025780 | Leucine rich repeat containing 66. | Transmembrane protein 156. | 0.445 |
N4BP2 | LIAS | ENSSTOP00000015390 | ENSSTOP00000001857 | NEDD4 binding protein 2. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.436 |
N4BP2 | PDS5A | ENSSTOP00000015390 | ENSSTOP00000011170 | NEDD4 binding protein 2. | PDS5 cohesin associated factor A. | 0.538 |
N4BP2 | TMEM156 | ENSSTOP00000015390 | ENSSTOP00000025780 | NEDD4 binding protein 2. | Transmembrane protein 156. | 0.448 |
PDS5A | LIAS | ENSSTOP00000011170 | ENSSTOP00000001857 | PDS5 cohesin associated factor A. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.447 |