IL1RAP protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IL1RAP

Interleukin 1 receptor accessory protein. (687 aa)

Predicted Functional Partners:

IL1B

0.995

IL1R1

0.995

IL1RL1

0.995

IL33

0.993

IL1RL2

0.990

PTPRD

0.986

IL1R2

0.972

IL1A

0.954

PTPRS

0.936

MYD88

0.934

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL1A	IL1B	ENSSTOP00000002041	ENSSTOP00000002047	Interleukin-1; Belongs to the IL-1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.996
IL1A	IL1R1	ENSSTOP00000002041	ENSSTOP00000015300	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.971
IL1A	IL1R2	ENSSTOP00000002041	ENSSTOP00000007622	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor type 2.	0.958
IL1A	IL1RAP	ENSSTOP00000002041	ENSSTOP00000026459	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.954
IL1A	IL1RL1	ENSSTOP00000002041	ENSSTOP00000020381	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor like 1.	0.894
IL1A	IL1RL2	ENSSTOP00000002041	ENSSTOP00000003717	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.948
IL1A	IL33	ENSSTOP00000002041	ENSSTOP00000025345	Interleukin-1; Belongs to the IL-1 family.	Interleukin 33.	0.452
IL1A	MYD88	ENSSTOP00000002041	ENSSTOP00000012227	Interleukin-1; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.817
IL1B	IL1A	ENSSTOP00000002047	ENSSTOP00000002041	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.996
IL1B	IL1R1	ENSSTOP00000002047	ENSSTOP00000015300	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.995
IL1B	IL1R2	ENSSTOP00000002047	ENSSTOP00000007622	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor type 2.	0.993
IL1B	IL1RAP	ENSSTOP00000002047	ENSSTOP00000026459	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.995
IL1B	IL1RL1	ENSSTOP00000002047	ENSSTOP00000020381	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor like 1.	0.943
IL1B	IL1RL2	ENSSTOP00000002047	ENSSTOP00000003717	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.975
IL1B	IL33	ENSSTOP00000002047	ENSSTOP00000025345	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 33.	0.541
IL1B	MYD88	ENSSTOP00000002047	ENSSTOP00000012227	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.830
IL1R1	IL1A	ENSSTOP00000015300	ENSSTOP00000002041	Interleukin 1 receptor type 1.	Interleukin-1; Belongs to the IL-1 family.	0.971
IL1R1	IL1B	ENSSTOP00000015300	ENSSTOP00000002047	Interleukin 1 receptor type 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.995
IL1R1	IL1R2	ENSSTOP00000015300	ENSSTOP00000007622	Interleukin 1 receptor type 1.	Interleukin 1 receptor type 2.	0.937
IL1R1	IL1RAP	ENSSTOP00000015300	ENSSTOP00000026459	Interleukin 1 receptor type 1.	Interleukin 1 receptor accessory protein.	0.995