STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101956162GLOBIN domain-containing protein; Belongs to the globin family. (142 aa)    
Predicted Functional Partners:
Hbe1
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.991
LOC101967841
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.991
LOC101969569
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.990
LOC101977640
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.990
LOC101976500
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
    
 0.989
LOC101967554
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.973
LOC101974084
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.945
HBQ1
Hemoglobin subunit theta 1; Belongs to the globin family.
  
0.916
CYB5R4
Cytochrome b5 reductase 4.
   
 0.738
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
     
 0.680
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.